ProteinPRS Polygenic Prediction of Plasma Protein Levels
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SPRED2

Olink Explore plasma protein · SNPBoost PRS model

Download PRS model
R2 Full Model
0.0098
pearson_coefficent
0.1036
sparsity
56
n_cis_pqtl
7
max_cis_pqtl
rs115394012

Diagnostics

PRS scatter and box plotsenlarge ⤢
PRS scatter and box plots for SPRED2
Genome-wide Manhattan Plotenlarge ⤢
Genome-wide Manhattan plot for SPRED2
Regional Manhattan Plotenlarge ⤢
Regional Manhattan plot for SPRED2

Model record

Field
Value
Gene
SPRED2
test_n
10538
sparsity
56
pearson_coefficent
0.103647769197711
SE
0.0108418085324944
P_corr
1.51451304190954e-21
R2 Covariate Model
-3e-04
R2 Full Model
0.0098
P
2.8803407733679e-22
P_full
5.90415724202612e-90
n_cis_pqtl
7
max_cis_pqtl
rs115394012
rank_max_cis_pqtl
3
mean_pqtl_beta
0.00507721642589626
mean_nopqtl_beta
0.0052548537277697
percentage_pqtl
0.125
percentage_nopqtl
0.875

cis and genome-wide metrics

Field
Value
Gene
SPRED2
test_n_genomewide
10538
sparsity_genomewide
56
pearson_coefficent_genomewide
0.103647769197711
SE_genomewide
0.0108418085324944
P_corr_genomewide
1.51451304190954e-21
R2_covariate_model_genomewide
-0.000273715751980097
R2_full_model_genomewide
0.00978225684551049
P_genomewide
2.8803407733679e-22
P_full_genomewide
5.90415724202612e-90
n_cis_pqtl
7
max_cis_pqtl
rs115394012
rank_max_cis_pqtl
3
mean_pqtl_beta
0.00507721642589626
mean_nopqtl_beta
0.0052548537277697
percentage_pqtl
0.125
percentage_nopqtl
0.875
test_n_cis
10538
sparsity_cis
7
pearson_coefficent_cis
0.0497309842666566
SE_cis
0.0108870302389777
P_corr_cis
4.99618581561612e-06
R2_covariate_model_cis
-0.000273715751980097
R2_full_model_cis
0.00197638046633453
P_cis
8.01638088970485e-07
P_full_cis
1.16003108112058e-18