ProteinPRS Polygenic Prediction of Plasma Protein Levels
← All proteins

HHEX

Olink Explore plasma protein · SNPBoost PRS model

Download PRS model
R2 Full Model
0.0599
pearson_coefficent
0.2197
sparsity
264
n_cis_pqtl
5
max_cis_pqtl
rs61746130

Diagnostics

PRS scatter and box plotsenlarge ⤢
PRS scatter and box plots for HHEX
Genome-wide Manhattan Plotenlarge ⤢
Genome-wide Manhattan plot for HHEX
Regional Manhattan Plotenlarge ⤢
Regional Manhattan plot for HHEX

Model record

Field
Value
Gene
HHEX
test_n
10538
sparsity
264
pearson_coefficent
0.219672787145332
SE
0.010493072275474
P_corr
5.68360136988511e-95
R2 Covariate Model
0.013
R2 Full Model
0.0599
P
1.53817951678737e-118
P_full
2.28905013817781e-304
n_cis_pqtl
5
max_cis_pqtl
rs61746130
rank_max_cis_pqtl
37
mean_pqtl_beta
0.00963459104019431
mean_nopqtl_beta
0.0088639449926697
percentage_pqtl
0.0189393939393939
percentage_nopqtl
0.981060606060606

cis and genome-wide metrics

Field
Value
Gene
HHEX
test_n_genomewide
10538
sparsity_genomewide
264
pearson_coefficent_genomewide
0.219672787145332
SE_genomewide
0.010493072275474
P_corr_genomewide
5.68360136988511e-95
R2_covariate_model_genomewide
0.0130353564178952
R2_full_model_genomewide
0.059868648965115
P_genomewide
1.53817951678737e-118
P_full_genomewide
2.28905013817781e-304
n_cis_pqtl
5
max_cis_pqtl
rs61746130
rank_max_cis_pqtl
37
mean_pqtl_beta
0.00963459104019431
mean_nopqtl_beta
0.0088639449926697
percentage_pqtl
0.0189393939393939
percentage_nopqtl
0.981060606060606
test_n_cis
10538
sparsity_cis
5
pearson_coefficent_cis
0.0451427363243105
SE_cis
0.010744832563206
P_corr_cis
2.68001644438682e-05
R2_covariate_model_cis
0.0130353564178952
R2_full_model_cis
0.0147046837201249
P_cis
5.68622452208125e-30
P_full_cis
6.1884227392023e-07