ProteinPRS Polygenic Prediction of Plasma Protein Levels
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GFAP

Olink Explore plasma protein · SNPBoost PRS model

Download PRS model
R2 Full Model
0.1905
pearson_coefficent
0.2275
sparsity
268
n_cis_pqtl
8
max_cis_pqtl
rs59291670

Diagnostics

PRS scatter and box plotsenlarge ⤢
PRS scatter and box plots for GFAP
Genome-wide Manhattan Plotenlarge ⤢
Genome-wide Manhattan plot for GFAP
Regional Manhattan Plotenlarge ⤢
Regional Manhattan plot for GFAP

Model record

Field
Value
Gene
GFAP
test_n
10538
sparsity
268
pearson_coefficent
0.22752323204719
SE
0.00974357442517759
P_corr
1.813915782672e-117
R2 Covariate Model
0.1462
R2 Full Model
0.1905
P
0
P_full
0
n_cis_pqtl
8
max_cis_pqtl
rs59291670
rank_max_cis_pqtl
2
mean_pqtl_beta
0.0264360377816503
mean_nopqtl_beta
0.00636608818125359
percentage_pqtl
0.0298507462686567
percentage_nopqtl
0.970149253731343

cis and genome-wide metrics

Field
Value
Gene
GFAP
test_n_genomewide
10538
sparsity_genomewide
268
pearson_coefficent_genomewide
0.22752323204719
SE_genomewide
0.00974357442517759
P_corr_genomewide
1.813915782672e-117
R2_covariate_model_genomewide
0.146214874724473
R2_full_model_genomewide
0.190457812703487
P_genomewide
0
P_full_genomewide
0
n_cis_pqtl
8
max_cis_pqtl
rs59291670
rank_max_cis_pqtl
2
mean_pqtl_beta
0.0264360377816503
mean_nopqtl_beta
0.00636608818125359
percentage_pqtl
0.0298507462686567
percentage_nopqtl
0.970149253731343
test_n_cis
10538
sparsity_cis
8
pearson_coefficent_cis
0.0968691403970633
SE_cis
0.00995894842583149
P_corr_cis
2.90803009774894e-22
R2_covariate_model_cis
0.146214874724473
R2_full_model_cis
0.154732364497943
P_cis
0
P_full_cis
3.95428515525738e-65