ProteinPRS Polygenic Prediction of Plasma Protein Levels
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CACNB3

Olink Explore plasma protein · SNPBoost PRS model

Download PRS model
R2 Full Model
0.0212
pearson_coefficent
0.1464
sparsity
71
n_cis_pqtl
15
max_cis_pqtl
rs11168749

Diagnostics

PRS scatter and box plotsenlarge ⤢
PRS scatter and box plots for CACNB3
Genome-wide Manhattan Plotenlarge ⤢
Genome-wide Manhattan plot for CACNB3
Regional Manhattan Plotenlarge ⤢
Regional Manhattan plot for CACNB3

Model record

Field
Value
Gene
CACNB3
test_n
10538
sparsity
71
pearson_coefficent
0.146384649407217
SE
0.0106399334145224
P_corr
1.27918777990033e-42
R2 Covariate Model
-5e-04
R2 Full Model
0.0212
P
1.20409815897318e-42
P_full
1.31348110287528e-148
n_cis_pqtl
15
max_cis_pqtl
rs11168749
rank_max_cis_pqtl
2
mean_pqtl_beta
0.0117104211946189
mean_nopqtl_beta
0.00891297748389877
percentage_pqtl
0.211267605633803
percentage_nopqtl
0.788732394366197

cis and genome-wide metrics

Field
Value
Gene
CACNB3
test_n_genomewide
10538
sparsity_genomewide
71
pearson_coefficent_genomewide
0.146384649407217
SE_genomewide
0.0106399334145224
P_corr_genomewide
1.27918777990033e-42
R2_covariate_model_genomewide
-0.000514749175601015
R2_full_model_genomewide
0.0212496014310509
P_genomewide
1.20409815897318e-42
P_full_genomewide
1.31348110287528e-148
n_cis_pqtl
15
max_cis_pqtl
rs11168749
rank_max_cis_pqtl
2
mean_pqtl_beta
0.0117104211946189
mean_nopqtl_beta
0.00891297748389877
percentage_pqtl
0.211267605633803
percentage_nopqtl
0.788732394366197
test_n_cis
10538
sparsity_cis
15
pearson_coefficent_cis
0.0994658607773852
SE_cis
0.0107024593270812
P_corr_cis
1.85485369096605e-20
R2_covariate_model_cis
-0.000514749175601015
R2_full_model_cis
0.00917829019764649
P_cis
4.13904025422014e-19
P_full_cis
6.034176355354e-50