ProteinPRS Polygenic Prediction of Plasma Protein Levels
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ASPN

Olink Explore plasma protein · SNPBoost PRS model

Download PRS model
R2 Full Model
0.1065
pearson_coefficent
0.2366
sparsity
336
n_cis_pqtl
16
max_cis_pqtl
rs3780340

Diagnostics

PRS scatter and box plotsenlarge ⤢
PRS scatter and box plots for ASPN
Genome-wide Manhattan Plotenlarge ⤢
Genome-wide Manhattan plot for ASPN
Regional Manhattan Plotenlarge ⤢
Regional Manhattan plot for ASPN

Model record

Field
Value
Gene
ASPN
test_n
10538
sparsity
336
pearson_coefficent
0.236564773540473
SE
0.0104408435188758
P_corr
1.82402795900509e-110
R2 Covariate Model
0.0509
R2 Full Model
0.1065
P
3.03744191337183e-214
P_full
0
n_cis_pqtl
16
max_cis_pqtl
rs3780340
rank_max_cis_pqtl
1
mean_pqtl_beta
0.00961327594709826
mean_nopqtl_beta
0.00336070881905793
percentage_pqtl
0.0476190476190476
percentage_nopqtl
0.952380952380952

cis and genome-wide metrics

Field
Value
Gene
ASPN
test_n_genomewide
10538
sparsity_genomewide
336
pearson_coefficent_genomewide
0.236564773540473
SE_genomewide
0.0104408435188758
P_corr_genomewide
1.82402795900509e-110
R2_covariate_model_genomewide
0.0508847863776
R2_full_model_genomewide
0.106457875532169
P_genomewide
3.03744191337183e-214
P_full_genomewide
0
n_cis_pqtl
16
max_cis_pqtl
rs3780340
rank_max_cis_pqtl
1
mean_pqtl_beta
0.00961327594709826
mean_nopqtl_beta
0.00336070881905793
percentage_pqtl
0.0476190476190476
percentage_nopqtl
0.952380952380952
test_n_cis
10538
sparsity_cis
16
pearson_coefficent_cis
0.152651928659608
SE_cis
0.0106199156490156
P_corr_cis
2.56038183170102e-46
R2_covariate_model_cis
0.0508847863776
R2_full_model_cis
0.0754892334703563
P_cis
5.97597579564841e-150
P_full_cis
4.9416638756877e-178