ProteinPRS Polygenic Prediction of Plasma Protein Levels
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APP

Olink Explore plasma protein · SNPBoost PRS model

Download PRS model
R2 Full Model
0.1554
pearson_coefficent
0.3862
sparsity
999
n_cis_pqtl
20
max_cis_pqtl
rs2000989

Diagnostics

PRS scatter and box plotsenlarge ⤢
PRS scatter and box plots for APP
Genome-wide Manhattan Plotenlarge ⤢
Genome-wide Manhattan plot for APP
Regional Manhattan Plotenlarge ⤢
Regional Manhattan plot for APP

Model record

Field
Value
Gene
APP
test_n
10538
sparsity
999
pearson_coefficent
0.386164108013441
SE
0.00911645308800846
P_corr
0
R2 Covariate Model
0.0066
R2 Full Model
0.1554
P
0
P_full
0
n_cis_pqtl
20
max_cis_pqtl
rs2000989
rank_max_cis_pqtl
4
mean_pqtl_beta
0.00978403469775939
mean_nopqtl_beta
0.00773779886948564
percentage_pqtl
0.02002002002002
percentage_nopqtl
0.97997997997998

cis and genome-wide metrics

Field
Value
Gene
APP
test_n_genomewide
10538
sparsity_genomewide
999
pearson_coefficent_genomewide
0.386164108013441
SE_genomewide
0.00911645308800846
P_corr_genomewide
0
R2_covariate_model_genomewide
0.00659967633847303
R2_full_model_genomewide
0.15536234908998
P_genomewide
0
P_full_genomewide
0
n_cis_pqtl
20
max_cis_pqtl
rs2000989
rank_max_cis_pqtl
4
mean_pqtl_beta
0.00978403469775939
mean_nopqtl_beta
0.00773779886948564
percentage_pqtl
0.02002002002002
percentage_nopqtl
0.97997997997998
test_n_cis
10538
sparsity_cis
20
pearson_coefficent_cis
0.0763316840613576
SE_cis
0.00985424879834081
P_corr_cis
1.0375636425006e-14
R2_covariate_model_cis
0.00659967633847314
R2_full_model_cis
0.0135068600733208
P_cis
3.93855824185016e-35
P_full_cis
1.03376026523422e-41