ProteinPRS Polygenic Prediction of Plasma Protein Levels
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VAMP8

Olink Explore plasma protein · SNPBoost PRS model

Download PRS model
R2 Full Model
0.0364
pearson_coefficent
0.1896
sparsity
184
n_cis_pqtl
12
max_cis_pqtl
rs3731828

Diagnostics

PRS scatter and box plotsenlarge ⤢
PRS scatter and box plots for VAMP8
Genome-wide Manhattan Plotenlarge ⤢
Genome-wide Manhattan plot for VAMP8
Regional Manhattan Plotenlarge ⤢
Regional Manhattan plot for VAMP8

Model record

Field
Value
Gene
VAMP8
test_n
10538
sparsity
184
pearson_coefficent
0.189642033862577
SE
0.0107027095541473
P_corr
5.30006038932046e-69
R2 Covariate Model
8e-04
R2 Full Model
0.0364
P
3.42431577617594e-70
P_full
8.46120937233164e-219
n_cis_pqtl
12
max_cis_pqtl
rs3731828
rank_max_cis_pqtl
1
mean_pqtl_beta
0.0236430646497812
mean_nopqtl_beta
0.00936532086285609
percentage_pqtl
0.0652173913043478
percentage_nopqtl
0.934782608695652

cis and genome-wide metrics

Field
Value
Gene
VAMP8
test_n_genomewide
10538
sparsity_genomewide
184
pearson_coefficent_genomewide
0.189642033862577
SE_genomewide
0.0107027095541473
P_corr_genomewide
5.30006038932046e-69
R2_covariate_model_genomewide
0.000810125040394794
R2_full_model_genomewide
0.0364480794848805
P_genomewide
3.42431577617594e-70
P_full_genomewide
8.46120937233164e-219
n_cis_pqtl
12
max_cis_pqtl
rs3731828
rank_max_cis_pqtl
1
mean_pqtl_beta
0.0236430646497812
mean_nopqtl_beta
0.00936532086285609
percentage_pqtl
0.0652173913043478
percentage_nopqtl
0.934782608695652
test_n_cis
10538
sparsity_cis
12
pearson_coefficent_cis
0.114897781170828
SE_cis
0.010828327362297
P_corr_cis
3.87913353779507e-26
R2_covariate_model_cis
0.000810125040394794
R2_full_model_cis
0.0132730546639462
P_cis
4.18827594701975e-27
P_full_cis
8.40291589711937e-94