ProteinPRS Polygenic Prediction of Plasma Protein Levels
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TGFB2

Olink Explore plasma protein · SNPBoost PRS model

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R2 Full Model
0.0077
pearson_coefficent
0.0715
sparsity
8
n_cis_pqtl
2
max_cis_pqtl
rs12044812

Diagnostics

PRS scatter and box plotsenlarge ⤢
PRS scatter and box plots for TGFB2
Genome-wide Manhattan Plotenlarge ⤢
Genome-wide Manhattan plot for TGFB2
Regional Manhattan Plotenlarge ⤢
Regional Manhattan plot for TGFB2

Model record

Field
Value
Gene
TGFB2
test_n
10538
sparsity
8
pearson_coefficent
0.0715405185364561
SE
0.0107313420982845
P_corr
2.78032400844905e-11
R2 Covariate Model
0.0025
R2 Full Model
0.0077
P
2.49878785645059e-16
P_full
1.24647035746174e-30
n_cis_pqtl
2
max_cis_pqtl
rs12044812
rank_max_cis_pqtl
1
mean_pqtl_beta
0.02320235435164
mean_nopqtl_beta
0.00550112985540821
percentage_pqtl
0.25
percentage_nopqtl
0.75

cis and genome-wide metrics

Field
Value
Gene
TGFB2
test_n_genomewide
10538
sparsity_genomewide
8
pearson_coefficent_genomewide
0.0715405185364561
SE_genomewide
0.0107313420982845
P_corr_genomewide
2.78032400844905e-11
R2_covariate_model_genomewide
0.00245170653299787
R2_full_model_genomewide
0.00766451120214451
P_genomewide
2.49878785645059e-16
P_full_genomewide
1.24647035746174e-30
n_cis_pqtl
2
max_cis_pqtl
rs12044812
rank_max_cis_pqtl
1
mean_pqtl_beta
0.02320235435164
mean_nopqtl_beta
0.00550112985540821
percentage_pqtl
0.25
percentage_nopqtl
0.75
test_n_cis
10538
sparsity_cis
2
pearson_coefficent_cis
0.0631006538045557
SE_cis
0.0107374690139372
P_corr_cis
4.34094460670792e-09
R2_covariate_model_cis
0.00245170653299798
R2_full_model_cis
0.00650728031547898
P_cis
3.40968429178476e-14
P_full_cis
5.95738199355725e-23