ProteinPRS Polygenic Prediction of Plasma Protein Levels
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REG3A

Olink Explore plasma protein · SNPBoost PRS model

Download PRS model
R2 Full Model
0.2109
pearson_coefficent
0.3954
sparsity
1192
n_cis_pqtl
81
max_cis_pqtl
rs4459759

Diagnostics

PRS scatter and box plotsenlarge ⤢
PRS scatter and box plots for REG3A
Genome-wide Manhattan Plotenlarge ⤢
Genome-wide Manhattan plot for REG3A
Regional Manhattan Plotenlarge ⤢
Regional Manhattan plot for REG3A

Model record

Field
Value
Gene
REG3A
test_n
10538
sparsity
1192
pearson_coefficent
0.395393038092821
SE
0.00901629296202171
P_corr
0
R2 Covariate Model
0.0668
R2 Full Model
0.2109
P
0
P_full
0
n_cis_pqtl
81
max_cis_pqtl
rs4459759
rank_max_cis_pqtl
2
mean_pqtl_beta
0.0146895250310822
mean_nopqtl_beta
0.00726634982652291
percentage_pqtl
0.0679530201342282
percentage_nopqtl
0.932046979865772

cis and genome-wide metrics

Field
Value
Gene
REG3A
test_n_genomewide
10538
sparsity_genomewide
1192
pearson_coefficent_genomewide
0.395393038092821
SE_genomewide
0.00901629296202171
P_corr_genomewide
0
R2_covariate_model_genomewide
0.066763425421494
R2_full_model_genomewide
0.210860076660549
P_genomewide
0
P_full_genomewide
0
n_cis_pqtl
81
max_cis_pqtl
rs4459759
rank_max_cis_pqtl
2
mean_pqtl_beta
0.0146895250310822
mean_nopqtl_beta
0.00726634982652291
percentage_pqtl
0.0679530201342282
percentage_nopqtl
0.932046979865772
test_n_cis
10538
sparsity_cis
81
pearson_coefficent_cis
0.181230326110372
SE_cis
0.00965364524595648
P_corr_cis
2.37088401862865e-77
R2_covariate_model_cis
0.066763425421494
R2_full_model_cis
0.099352694436743
P_cis
1.92447765163047e-239
P_full_cis
2.54085085947221e-280