ProteinPRS Polygenic Prediction of Plasma Protein Levels
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ICA1

Olink Explore plasma protein · SNPBoost PRS model

Download PRS model
R2 Full Model
0.0437
pearson_coefficent
0.2087
sparsity
182
n_cis_pqtl
9
max_cis_pqtl
rs111304183

Diagnostics

PRS scatter and box plotsenlarge ⤢
PRS scatter and box plots for ICA1
Genome-wide Manhattan Plotenlarge ⤢
Genome-wide Manhattan plot for ICA1
Regional Manhattan Plotenlarge ⤢
Regional Manhattan plot for ICA1

Model record

Field
Value
Gene
ICA1
test_n
10538
sparsity
182
pearson_coefficent
0.208665079074345
SE
0.00974195178624726
P_corr
1.43669914214807e-99
R2 Covariate Model
0
R2 Full Model
0.0437
P
2.71577124149604e-100
P_full
4.46561942232228e-253
n_cis_pqtl
9
max_cis_pqtl
rs111304183
rank_max_cis_pqtl
5
mean_pqtl_beta
0.00884741723183407
mean_nopqtl_beta
0.00993158868779019
percentage_pqtl
0.0494505494505495
percentage_nopqtl
0.950549450549451

cis and genome-wide metrics

Field
Value
Gene
ICA1
test_n_genomewide
10538
sparsity_genomewide
182
pearson_coefficent_genomewide
0.208665079074345
SE_genomewide
0.00974195178624726
P_corr_genomewide
1.43669914214807e-99
R2_covariate_model_genomewide
3.24085838299126e-05
R2_full_model_genomewide
0.0437268724122071
P_genomewide
2.71577124149604e-100
P_full_genomewide
4.46561942232228e-253
n_cis_pqtl
9
max_cis_pqtl
rs111304183
rank_max_cis_pqtl
5
mean_pqtl_beta
0.00884741723183407
mean_nopqtl_beta
0.00993158868779019
percentage_pqtl
0.0494505494505495
percentage_nopqtl
0.950549450549451
test_n_cis
10538
sparsity_cis
9
pearson_coefficent_cis
0.0303692549681964
SE_cis
0.0099566320393517
P_corr_cis
0.00229318673957703
R2_covariate_model_cis
3.24085838299126e-05
R2_full_model_cis
0.000772969351100383
P_cis
4.83750344201089e-05
P_full_cis
3.91147796560482e-12