ProteinPRS Polygenic Prediction of Plasma Protein Levels
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AOC1

Olink Explore plasma protein · SNPBoost PRS model

Download PRS model
R2 Full Model
0.0255
pearson_coefficent
0.1638
sparsity
70
n_cis_pqtl
6
max_cis_pqtl
rs1049742

Diagnostics

PRS scatter and box plotsenlarge ⤢
PRS scatter and box plots for AOC1
Genome-wide Manhattan Plotenlarge ⤢
Genome-wide Manhattan plot for AOC1
Regional Manhattan Plotenlarge ⤢
Regional Manhattan plot for AOC1

Model record

Field
Value
Gene
AOC1
test_n
10538
sparsity
70
pearson_coefficent
0.163790859912544
SE
0.00982670116497809
P_corr
1.48959785707288e-61
R2 Covariate Model
-0.0012
R2 Full Model
0.0255
P
5.2344692535924e-59
P_full
1.27625097111306e-195
n_cis_pqtl
6
max_cis_pqtl
rs1049742
rank_max_cis_pqtl
2
mean_pqtl_beta
0.0403053984697441
mean_nopqtl_beta
0.0126097557262883
percentage_pqtl
0.0857142857142857
percentage_nopqtl
0.914285714285714

cis and genome-wide metrics

Field
Value
Gene
AOC1
test_n_genomewide
10538
sparsity_genomewide
70
pearson_coefficent_genomewide
0.163790859912544
SE_genomewide
0.00982670116497809
P_corr_genomewide
1.48959785707288e-61
R2_covariate_model_genomewide
-0.00124267124127053
R2_full_model_genomewide
0.0254983020115724
P_genomewide
5.2344692535924e-59
P_full_genomewide
1.27625097111306e-195
n_cis_pqtl
6
max_cis_pqtl
rs1049742
rank_max_cis_pqtl
2
mean_pqtl_beta
0.0403053984697441
mean_nopqtl_beta
0.0126097557262883
percentage_pqtl
0.0857142857142857
percentage_nopqtl
0.914285714285714
test_n_cis
10538
sparsity_cis
6
pearson_coefficent_cis
0.143377906163502
SE_cis
0.00985830741289041
P_corr_cis
1.92864130305323e-47
R2_covariate_model_cis
-0.00124267124127053
R2_full_model_cis
0.0191876916149948
P_cis
4.7239806406031e-45
P_full_cis
1.67312423215505e-161